Figure 4. Increased susceptibility to DSS-induced colitis in CX3CR1-deficient mice.
(A) Severity of colitis in DSS-treated Cx3cr1gfp/gfp and Cx3cr1–/– mice or their respective Cx3cr1+/+ age- and vendor-matched control mice, as measured by stool consistency, presence of fecal blood, and weight loss. (B) Colon histology of DSS-treated Cx3cr1gfp/gfp, Cx3cr1–/–, and Cx3cr1+/+ mice. Original magnification, ×400. Data are representative of 3 independent experiments. Error bars represent SEM. *P < 0.05.