Table 2.

Surviving Sepsis Campaign: sepsis resuscitation bundle

Step	Details
1	Serum lactate measured
2	Blood cultures obtained before antibiotic administration
3	From the time of presentation, broad-spectrum antibiotics administered within 3 hours for ED admissions and 1 hour for non-ED intensive care unit admissions
4	In the event of hypotension and/or lactate >4 mmol/l (36 mg/dl):
	Deliver an initial minimum of 20 ml/kg of crystalloid (or colloid equivalent)
	Apply vasopressors for hypotension not responding to initial fluid resuscitation to maintain mean arterial pressure >65 mmHg
5	In the event of persistent hypotension despite fluid resuscitation (septic shock) and/or lactate >4 mmol/l (36 mg/dl):
	Achieve central venous pressure >8 mmHg
	Achieve central venous oxygen saturation >70%

ED, emergency department.