Table 4.
Levels for electrolytes, glucose, renal function tests, and liver function tests to assess for safety in 16 volunteers at week one and week six of study.
| Parameters | Week one mean (SD) | Week six mean (SD) | Mean difference (SD) | 95% Confidence interval | P value |
|---|---|---|---|---|---|
| Sodium (mmol/L) | 138.75 | 140.25 | −1.50 (4.62) | −3.96, 0.96 | .21 |
| Potassium (mmol/L) | 4.19 | 4.32 | −0.12 (0.40) | −0.34, 0.09 | .23 |
| Calcium (mmol/L) | 2.34 | 2.31 | 0.03 (0.17) | −0.06, 0.12 | .53 |
| Phosphate (mmol/L) | 1.24 | 1.18 | 0.06 (0.21) | −0.05, 0.17 | .27 |
| Uric acid (mmol/L) | 276.56 | 257.12 | 19.44 (37.75) | −0.68, 39.55 | .06 |
| Glucose (mmol/L) | 4.58 | 4.40 | 0.18 (0.56) | −0.12, 0.48 | .21 |
| Urea (mmol/L) | 4.39 | 4.38 | 0.01 (1.08) | −0.56, 0.59 | .96 |
| Creatinine (μmol/L) | 88.62 | 82.62 | 6.00 (5.19) | 3.23, 8.76 | <.001 |
| Albumin (g/dL) | 44.62 | 44.50 | 0.12 (2.09) | −0.99, 1.24 | .80 |
| Total bilirubin (μmol/L) | 7.87 | 8.25 | −0.37 (3.50) | −2.24, 1.49 | .67 |
| AST (U/L) | 21.06 | 19.31 | 1.75 (3.59) | −0.16, 3.66 | .07 |
| ALT (U/L) | 26.56 | 23.50 | 3.06 (4.40) | 0.72, 5.41 | .01 |
| ALP (U/L) | 70.19 | 71.19 | −1.00 (6.33) | −4.37, 2.37 | .54 |
*P value is significant when P < .05, SD = standard deviation.