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. 2011 Nov 17;2011:578273. doi: 10.1155/2011/578273

Figure 4.

Figure 4

Effect of diazepam on isolated retrograde perfused female guinea pig hearts (868 ± 45 g). After a minimum of 30 min stabilization, the hearts underwent 20 min of baseline recording. Subsequently the hearts were exposed to diazepam at increasing concentrations in 20 min intervals. Diazepam induced a dose-dependent reduction of heart rate and significantly shortened the heart rate at 30 μM (n = 5).