Table 3.
Effect of the methanolic extract of Lavandula officinalis on the onset and duration of sleep in thiopental-treated mice. Mice received thiopental (60 mg/kg, i.p.) 30 min after the pretreatment of methanolic extract (800 and 1000 mg/kg, p.o.) and diazepam (3 mg/kg, i.p.). i.p. means intraperitoneal route; p.o. means oral route; (n = 5) means number of mice per group; ME means methanolic extract; D ZP means diazepam. Data are expressed as mean ± SD; P < 0.001 versus the control group.
| Group | Dose (mg/kg) | Sleep latency (min) | Sleeping time (min) |
|---|---|---|---|
| Normal | 60 | 8 ± 1 | 36 ± 3 |
| DZP | 3 | 6 ± 1* | 75 ± 3* |
| ME | 800 | 12 ± 0.5* | 45 ± 2* |
| ME | 1000 | 6 ± 1* | 112 ± 3* |