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. 2011 Sep 19;194(6):815–824. doi: 10.1083/jcb.201102090

Figure 1.

Figure 1.

mTORC1 and cell migration. S6K1 and 4E-BP1 control cell motility by regulating (1) F-actin reorganization, (2) focal adhesion formation, (3) MMP-9 up-regulation (4) Rho expression and activity, and (5) VEGF and TGF-β expression in various cell types.