TABLE 1.

Transporter mRNA expression levels (relative to GAPDH) in cultured epithelial cells

Results are n = 3 repeats.

Cell Line	BCRP (ABCG2)	bcrp1 (abcg2)	MRP4 (ABCC4)
WT-MDCKII	0.71 ± 0.16
bcrp1-MDCKII	0.02 ± 0.01	3803.80 ± 504.12
BCRP-MDCKII	20389.59 ± 377.91
WT-HEK293			0.42 ± 0.05
MRP4-HEK293			94.67 ± 2.39
Low PA Caco-2	26.87 ± 0.69		2.12 ± 0.18
High PA Caco-2	0.43 ± 0.08		0.08 ± 0.01