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. 2011 Dec;39(12):2182–2190. doi: 10.1124/dmd.111.040212

Fig. 2.

Fig. 2.

Maximum steady-state plasma concentrations for silymarin flavonolignans at 560 mg of silymarin in HCV (■) and NAFLD (□) subjects. Plasma concentrations of isosilybin A, isosilybin B, silychristin, and silydianin were significantly greater in NAFLD subjects compared with HCV subjects. Silychristin and silydianin were not detected in the plasma of HCV subjects.