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Slopes of the standard curves for the substrate and metabolite pairs. The standard curves (analyte area/internal standard area versus analyte concentration/internal standard concentration) were prepared from the LC-MS analysis using at least four concentrations of substrate and metabolite. The error bar represents the S.D. All slopes except those for compounds 10 and 20 are significantly different at the 95% confidence limit. A, results for ESI. B, results for CSI.
