Table III. Three sequence variations in ANXA2 gene differentially distributed in low vs. high BMD subjects in sample 3. All subjects with low BMD were diagnosed as having osteopenia or osteoporosis. Exact chi-square test's were used to calculate the difference in frequency distribution. BMD: bone mineral density.
Sequence Variation | Group | Genotype & Frequency | P-Value | ||
---|---|---|---|---|---|
rs12909425 | TT | TC | CC | ||
Low BMD | 3 | 14 | 3 | 0.009 | |
High BMD | 1 | 8 | 13 | ||
rs11631777 | GG | GA | AA | ||
Low BMD | 0 | 1 | 21 | 0.029 | |
High BMD | 2 | 5 | 15 | ||
rs62004988 | AA | AG | GG | ||
Low BMD | 0 | 13 | 9 | 0.041 | |
High BMD | 2 | 6 | 14 |