Table 2.
Metabolic parameters
| Variable | Control | DM+NS | Pre-treatment | DM+LC(L) | DM+LC(H) |
|---|---|---|---|---|---|
| Body Weight (g) | 44.4 ± 3.4 | 40.1 ± 2.1 | 32.0 ± 2.8××## | 40.3 ± 2.0 | 41.8 ± 5.6 |
| Liver weight (g) | 1.3 ± 0.3 | 2.4 ± 0.5** | 2.0 ± 0.4* | 1.9 ± 0.3*# | 1.8 ± 0.2# |
| Relative liver weight | 0.04 ± 0.01 | 0.06 ± 0.01** | 0.06 ± 0.01 | 0.05 ± 0.00# | 0.05 ± 0.00## |
| FFA in liver (L/g·cm) | 1.7 ± 0.1 | 2.0 ± 0.3* | 1.8 ± 0.2 | 1.9 ± 0.3 | 1.8 ± 0.1 |
| TG in liver (mmol/L) | 0.23 ± 0.04 | 1.16 ± 0.6** | 0.34 ± 0.2## | 0.55 ± 0.09# | 0.48 ± 0.1## |
| TG in plasma (mmol/L) | 1.2 ± 0.1 | 3.9 ± 2.3** | 1.7 ± 0.6 | 2.2 ± 1.0 | 1.6 ± 0.4 |
| LC in liver (μmol/L) | 16.9 ± 3.4 | 11.2 ± 2.6* | 12.1 ± 3.1 | 14.9 ± 1.9 | 12.6 ± 4.1 |
| ALC in liver (μmol/L) | 1.0 ± 0.2 | 0.8 ± 0.3 | 1.0 ± 0.7 | 1.4 ± 0.2 | 2.3 ± 0.9**## |
| LC/ALC | 16.9 ± 4.7 | 16.6 ± 5.9 | 15.4 ± 6.6 | 11.3 ± 2.8 | 5.6 ± 1.5**## |
Control: control group, DM+NS: diabetic group, pre-treatment: preventive group, DM+LC (L): low-dose therapeutic group, DM+LC (H): high-dose therapeutic group. All values are expressed as the mean ± S.E. using the repeated measures method. *P < 0.05, **P < 0.01 (compared to control group), #P < 0.05, ##P < 0.01 (compared to diabetic group).