Table 3. Effect of cytokine gene dose on severity of pulmonary tuberculosis.

Cytokines	SNP Position	Genotypes	PTB (102)	PMN+PMD (74)	PAD (23)
			P-values	P-values	P-values
IFNγ	(+874) T→A	Additive	0.046	0.003
		Dominant		0.026
		Recessive	0.021	0.001
		Multiplicative	0.018	0.001
IL-10	(−1082) G→A	Additive			0.041
		Dominant			0.03
		Recessive
		Multiplicative
TNFα	(−308) A→G	Additive
		Dominant
		Recessive
		Multiplicative
IL-6	(−174) G→C	Additive
		Dominant
		Recessive	0.041
		Multiplicative	0.043

Note: Abbreviations for groups are as described in table 1. Group N is given in brackets.

Groups were compared with TBNA. Pearson χ2 or Fisher exact test was performed to determine group differences. Linear by linear corrected p values are shown.