Table 1. Patient characteristics.
Patient | Gender (Age) | Bacterium | Focal infection | Underlying disorders | Antiplatelet medication | SIRS signs on day of admittance | SIRS signs on day of experiment |
1 | F (76) | S. aureus | Cutaneous carbuncle | DM (type II) | - | 2/4 | 0/4 |
2 | M (77) | S. aureus | Pneumonia | COPD, CHF | A, C | 2/4 | 2/4 |
3 | M (72) | S. aureus | Septic arthritis | COPD, vasculitis | - | 2/4 | 2/4 |
4 | M (73) | S. aureus | Cellulitis | Colon cancer | - | 0/3 | 0/4 |
5 | M (39) | S. aureus | Unknown | Nephrostomy, Colostomy | - | 1/3 | 1/4 |
6 | M (23) | S. aureus | IE | Dermatitis | - | 2/4 | 0/3 |
7 | F (65) | S. aureus | Pneumonia | DM (type II) | A | 1/1 | 1/4 |
8 | M (91) | S. aureus | In diabetic leg ulcers | DM (type II) | A | 2/4 | 1/4 |
9 | F (42) | S. aureus | Pacemaker endocarditis | Pacemaker | - | 1/3 | 0/4 |
10 | M (77) | S. aureus | Unknown | CHF | A, C | 1/3 | 0/4 |
11 | F (98) | S. aureus | IE | Nasal cavity cancer, CHF | - | 3/3 | 1/4 |
12 | M (59) | S. aureus | Unknown | CMT | - | 2/3 | 1/4 |
13 | F (84) | S. aureus | IE | Pacemaker, CHF, PBC | - | 2/3 | 0/4 |
14 | M (71) | S. pneumoniae | Septic arthritis | DM (type I) | A | 2/4 | 0/1 |
15 | M (49) | S. pneumoniae | Pneumonia | None | - | 4/4 | 3/4 |
16 | F (65) | S. pneumoniae | Pneumonia | COPD | I | 0/1 | 1/4 |
17 | M (87) | S. pneumoniae | Pneumonia | None | A | 1/4 | 0/4 |
18 | F (58) | S. pneumoniae | Pneumonia | COPD, Asthma | - | 2/4 | 1/3 |
19 | F (74) | S. pneumoniae | Pneumonia | COPD | - | 2/4 | 0/4 |
20 | F (42) | S. pneumoniae | Pneumonia | None | - | 1/4 | 4/4 |
21 | M (39) | S. pneumoniae | Acute sinusitis | None | - | 1/4 | 0/4 |
22 | F (57) | S. pneumoniae | Unknown | None | - | 2/4 | 3/4 |
23 | F (67) | S. pneumoniae | Pneumonia | DM (type II) | A | 2/3 | 2/4 |
24 | F (64) | GAS | Septic arthritis | None | - | 2/3 | 2/4 |
25 | M (84) | GGS | In necrotic foot ulcers | Necrotic foot ulcers | - | 1/4 | 1/4 |
26 | M (88) | GGS | In chronic leg ulcers | Chronic leg ulcers | - | 2/4 | 2/4 |
27 | F (40) | GAS | Para-pharyngeal abscesses | None | - | 2/3 | 2/4 |
28 | M (75) | GAS | Wound infection | DM (type II), Urinary bladder cancer | - | 2/4 | 0/4 |
29 | M (75) | GAS | Septic arthritis | None | - | 3/4 | 2/3 |
30 | M (80) | E. faecalis | Unknown | DM (type II) | A | 2/2 | 0/4 |
31 | M (74) | E. faecalis | IE | Prosthetic heart valve | A | 2/4 | 0/4 |
32 | M (84) | E. faecalis | Unknown | Long-term indwelling catheter, COPD | A | 1/4 | 1/4 |
33 | M (73) | E. faecalis | Pyelitis | Prostatic hypertrophy | A | 4/4 | 1/4 |
34 | F (71) | E. faecium | Post-surgical abdominal infection | Gastro-intestinal carcinoid | A, I | 2/2 | 0/4 |
35 | M (67) | S. mutans | IE, Infectious spondylitis | None | - | 0/4 | 0/4 |
36 | F (74) | S. gordonii | IE | Prosthetic heart valve | - | 2/4 | 0/4 |
37 | M (48) | S. mitis | IE | Mitral insufficiency | - | 0/4 | 1/4 |
38 | F (74) | GBS | Erysipelas | Lymphedema | - | 2/4 | 0/4 |
Abbreviations: M = Male. F = Female. SIRS = systemic inflammation response syndrome. Numbers are given as the parameters fulfilled by the number parameters registered. For definitions, see the text.
IE = Infectious endocarditis. DM = Diabetes mellitus. COPD = Chronic Obstructive Pulmonary Disease. CHF = Congestive heart failure. CMT = Charcot-Marie-Tooth Disease. PBC = Primary biliary cirrhosis.
GAS = Group A streptococcus. GGS = Group G streptococcus. GBS = Group B streptococcus. A = Aspirin. C = Clopidogrel. I = Ibuprofen.