Table 1.
Baseline group statistics of FRDA patients and healthy controls
| Parameter | FRDA (n = 16) | controls (n = 16) |
|---|---|---|
| Age [yr] | 43.8 ± 9.3 (28-59) | 43.1 ± 8.7 (28-60) |
| Gender (male/female) | 10/6 | 10/6 |
| Height [m] | 1.72 ± 0.1 (1.59-1.83) | 1.73 ± 0,1 (1.57-1.89) |
| Weight [kg] | 73.9 ± 9.9 (58-95) | 74.8 ± 9 (56-94) |
| BSA [m2] | 1.89 ± 0,2 (1.61-2.20) | 1.9 ± 0.2 (1.61-2.16) |
| GAA shorter allel * | 402 ± 127 (220-560) | -- |
| GAA larger allel * | 798.5 ± 250.6 (250-1110) | -- |
| GAA product both alleles * |
394492.9 ± 245596.8 (62500-954600) |
-- |
| Onset of the disease [yr] | 17.2 ± 5.9 (7-30) | -- |
| Disease duration [yr] | 26.7 ± 8.7 (8-42) | -- |
| SARA | 26.5 ± 7 (9.5-36) | -- |
Values are given as mean ± SD; range (min-max) in brackets; Abbreviations: BSA - body surface area, yr - years, SARA - scale for the assessment and rating of ataxia. *Exact GAA allel length was available for n = 14