Figure 3. Cyclopamine alone impedes ovarian tumor growth.

Mice bearing human papillary serous ovarian tumor xenografts from sample SOC11 were randomized into 2 cohorts with matched tumor volumes and treated with either vehicle or cyclopamine. Tumor volumes were assessed regularly. Change in tumor volume is shown relative to the tumor volume at the beginning of the experiment. Error bars represent the standard error of the mean (S.E.M). The significance was determined using a Wilcoxon rank sum test.