Table 2. Correlation of Treg with Cell-Mediated Immunity, Plasma Inflammatory Factors and Other Cytokines and Tact in HIV-Infected and Uninfected Pregnant Women.
Variable (%) | VZV | Neopt | IL8 | IFNγ | IL4 | IL10 | CD4+ | CD8+ |
cpm | µg/ml | pg/ml | pg/ml | pg/ml | pg/ml | act | act | |
HIV-INFECTED WOMEN | ||||||||
CD4+CD25+FoxP3+ | -0.19* | 0.13 | 0.52 | 0.52 | 0.66 | 0.32 | 0.27 | -0.58 |
CD8+CD25+FoxP3+ | -0.08 | 0.45 | 0.50 | 0.51 | 0.31 | 0.48 | 0.14 | -0.32 |
CD4+IL10+ | 0.29 | 0.60 | 0.36 | 0.48 | 0.50 | 0.48 | 0 | 0.28 |
CD8+IL10+ | -0.05 | 0.30 | 0.48 | 0.48 | 0.28 | 0.19 | 0.38 | 0.13 |
CD4+TGFβ+ | -0.17 | 0.20 | 0.18 | 0.08 | 0.22 | 0.60 | -0.54 | -0.03 |
CD8+TGFβ+ | -0.65 | -0.03 | 0.58 | 0.39 | 0.40 | 0.36 | -0.47 | 0.09 |
CD4+FoxP3+ | -0.70 | -0.13 | 0.32 | 0.18 | 0.04 | 0.09 | -0.37 | -0.10 |
CD8+FoxP3+ | -0.57 | -0.12 | 0.35 | 0.19 | 0.06 | -0.06 | -0.38 | -0.09 |
CD4+CTLA4+ | 0.49 | 0.21 | 0.11 | 0 | 0.19 | 0.08 | 0.05 | 0.07 |
CD8+CTLA4+ | 0.22 | 0.22 | 0.23 | 0 | 0.27 | -0.28 | 0.08 | 0.02 |
UNINFECTED WOMEN | ||||||||
CD4+CD25+FoxP3+ | -0.16 | 0.19 | -0.12 | 0 | 0.28 | 0.25 | -0.69 | 0.01 |
CD8+CD25+FoxP3+ | -0.12 | -0.54 | 0.27 | -0.10 | 0.35 | 0.52 | -0.46 | 0.21 |
CD4+IL10+ | -0.09 | 0.25 | -0.22 | 0.45 | -0.20 | -0.14 | 0.28 | 0.20 |
CD8+IL10+ | -0.03 | 0.10 | -0.10 | 0.11 | -0.06 | 0 | -0.03 | 0 |
CD4+TGFβ+ | 0.12 | 0.06 | 0.31 | -0.07 | 0.16 | 0.06 | -0.35 | 0.30 |
CD8+TGFβ+ | -0.26 | 0.28 | -0.23 | -0.03 | 0.16 | 0.4 | -0.58 | 0.09 |
CD4+FoxP3+ | 0.20 | 0.11 | 0.35 | -0.45 | 0.04 | 0.25 | -0.67 | -0.58 |
CD8+FoxP3+ | -0.22 | -0.10 | 0.11 | 0.08 | 0.17 | 0.07 | -0.30 | -0.09 |
CD4+CTLA4+ | -0.17 | 0.59 | 0.08 | 0.24 | 0 | 0.21 | 0.02 | -0.37 |
CD8+CTLA4+ | 0.15 | 0.39 | -0.08 | 0.17 | -0.19 | -0.07 | 0.14 | -0.34 |
*Numbers represent Spearman correlation coefficients. Bold-facing and underscore indicates significant associations, with p<0.05; bold-facing and italics indicates marginally significant associations with p values of 0.05 to 0.1.