Table 1.
Descriptive characteristics of the cataract analysis cohort
| Males | Females | Overall | |
|---|---|---|---|
| Subjects (n %) | 7,031 43% | 9,305 57% | 16,336 |
| Cataracts (n %) | 1437 20% | 2167 23% | 3604 22% |
| Median age of onset (yr) | 67.1 | 65.6 | 66.2 |
| Minimum | 19 | 13 | 13 |
| Maximum | 90 | 90 | 90 |
| Type1 (%) | |||
| Nuclear | 96.8% | 97.1% | 97.0% |
| Cortical | 65.6% | 72.1% | 69.5% |
| Posterior subcapsular cataract (PSC) | 33.5% | 35.9% | 34.9% |
| Cataract surgery (n %) | 681 10% | 1118 12% | 1799 11% |
| Median age (yr) | 56.0 | 54.9 | 55.4 |
| Minimum | 30 | 30 | 30 |
| Maximum | 99 | 98 | 99 |
| Diabetes (n %) | 1243 18% | 1305 14% | 2548 16% |
| Smoking history (n %) | |||
| Never | 3061 44% | 5518 59% | 8579 53% |
| Current | 1255 18% | 1427 15% | 2682 16% |
| Other or unknown | 2715 39% | 2360 25% | 5075 31% |
| Steroid use (n %) | 1099 16% | 1545 17% | 2644 16% |
| Statin use (n %) | 2718 39% | 2684 29% | 5402 33% |
| Median BMI (kg/m2) | 28.8 | 28.0 | 28.4 |
| Minimum | 17.6 | 15.1 | 15.1 |
| Maximum | 60.1 | 74.9 | 74.9 |
| Median adjusted HDL (mg/dL)2 | 46.1 | 58.4 | 52.6 |
| Minimum | 19.8 | 22.7 | 19.8 |
| Maximum | 112.0 | 118.3 | 118.3 |
| Deceased (n %) | 456 6% | 376 4% | 832 5% |
1Cataract type available for 2719 subjects with cataract (1610 female, 1109 male.) Subjects may exhibit multiple types.
2 High density lipoprotein (HDL) results were limited to those prior to treatment with statins and prior to diagnosis with a condition known to affect HDL (e.g. thyroid disorders), and were subsequently adjusted for age and body size (body mass index =BMI). At least 2 results were required, and these were available for 7733 subjects (47%).