Table 6. Selection of growth-compensated mutants from an SCV in two steps.
SCV mutations | MIC (µg/ml) | |||
Strain | rplF | menB | KAN | FA |
AH001 | WT | WT | 2 | 0.064 |
AH386 | −A nt 90 | Gln204UAG (Stop) | 256 | 12 |
AH483 | −A nt 90 | Stop204Gln (WT) | 16 | 3 |
AH562 | +A nt 90 Lys (AAA = WT) | WT | 2 | 0.064 |
AH563 | +G nt 90 Lys (AAG) | WT | 2 | 0.064 |