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. Author manuscript; available in PMC: 2011 Nov 30.
Published in final edited form as: J Nucl Med. 2008 Dec;49(12):2018–2025. doi: 10.2967/jnumed.108.054262

TABLE 2.

Rate Constants and Calculated VT for 2-Parameter Compartment Model and Logan Graphic Analysis

Region Mean ± SD
Minimum scan
duration (min)
K1 (mL/min/g) k2 (1/min) VT (mL/g) VT (graphic)
Cerebellum 0.77 ± 0.46 0.12 ± 0.07 6.3 ± 1.6 4.5 ± 1.7 25
Cingulate cortex 0.65 ± 0.2 0.06 ± 0.02 10.6 ± 2.8 6.9 ± 1.6 35
Dorsal raphe 0.58 ± 0.17 0.02 ± 0.01 31.2 ± 11.9 17.7 ± 6.7 35
Amygdalae 0.48 ± 0.17 0.03 ± 0.01 15.3 ± 4.6 9.3 ± 2.2 65
Caudate nucleus 0.84 ± 0.29 0.05 ± 0.02 17.7 ± 4.8 11.2 ± 2.7 35
Frontal cortex 0.77 ± 0.42 0.09 ± 0.05 9.1 ± 3.0 5.9 ± 1.5 35
Occipital cortex 0.65 ± 0.32 0.07 ± 0.03 9.0 ± 3.0 5.9 ± 1.9 45
Pulvinar thalamus 0.73 ± 0.22 0.03 ± 0.01 23.3 ± 6.2 14.4 ± 3.9 35
Putamen 0.89 ± 0.33 0.05 ± 0.02 19.0 ± 5.1 12.0 ± 2.5 35
Magnus raphe 0.55 ± 0.19 0.03 ± 0.01 17.6 ± 5.7 10.7 ± 3.3 35
Hypothalamus 0.65 ± 0.21 0.02 ± 0.01 28.4 ± 8.9 17.8 ± 6.8 45
Midbrain 0.61 ± 0.17 0.02 ± 0.00 29.4 ± 9.9 17.2 ± 5.5 45
Pons 0.56 ± 0.24 0.06 ± 0.02 9.6 ± 3.3 6.1 ± 2.2 35
Pallidus raphe 0.52 ± 0.16 0.03 ± 0.01 17.1 ± 6.3 10.5 ± 4.1 45