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IRBP protects the isomeric state of 11-cis-retinol. 11-cis-Retinol (10 μm) was exposed to light in the presence or absence of IRBP. In control conditions (no carrier), the addition of light caused a significant reduction in the levels of 11-cis-retinol extracted (n = 4; p = 0.008). In the presence of IRBP (15 μm), exposure to light had no effect on 11-cis-retinol levels (n = 4; p = 0.59). Thus, IRBP protects 11-cis-retinol from photodegradation. Data points represent means ± 1 SD.
