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. 2011 Sep 28;31(39):13870–13879. doi: 10.1523/JNEUROSCI.2652-11.2011

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Copyright © 2011 the authors 0270-6474/11/3113870-10$15.00/0

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Figure 5. — Quintuple mutant eliminates potentiation by 3 μm PNU. Single-channel current traces and dwell time histograms from quintuple (SLMF+S223T) and single (S223T; S223V; S223A) mutant α7 receptors in the absence (left) and presence (right) of 3 μm PNU in the pipette solution. Openings were elicited by 100 μm ACh, and all recordings were made in the cell-attached patch configuration with an applied voltage of −70 mV. Openings are upward deflections, and all traces are shown at a bandwidth of 5 kHz.