Table 2.
Macroscopic and intrinsic binding constants, K20 and Kin, and the site-size, n, characterizing the binding of the PriB protein to different ssDNA homo-oligomers, dN(pN)19, in buffer C (pH 7.0, 10 °C). The values of K20 for the unmodified 20-mers have been determined using the MCT Method (details in text).*
| dεA(pεA)19 | dA(pA)19 | dT(pT)19 | dC(pC)19 | |
|---|---|---|---|---|
| K20 (M−1) | (1.7 ± 0.4) × 106 | (3.5 ± 0.8) × 105 | (3.0 ± 0.7) × 108 | (2.5 ± 0.4) × 107 |
| Kin (M−1) | (1.9 ± 0.5) × 105 | (3.9 ± 0.8) × 104 | (3.3 ± 0.7) × 107 | (2.8 ± 0.4) × 106 |
| n | 12 | 12 | 12 | 12 |
Errors are standard deviations determined using 3–4 independent titration experiments.