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. Author manuscript; available in PMC: 2012 Nov 22.
Published in final edited form as: J Am Coll Cardiol. 2011 Nov 22;58(22):2270–2278. doi: 10.1016/j.jacc.2011.08.041

Table 2.

List of miRs differentially expressed (p<0.05) on screening microarray, and confirmation of expression by individual Taqman Real-Time PCR with pre-amplification.Fold change refers to Recovered (R)/Dependent (D) ratio. A negative number indicates lower expression in the Recovered group compared with Dependent. Of the 10 miRs found differentially expressed by screening array, miRs-15b, -23a, -26a, and -195 showed decreased expression by confirmatory PCR. Of these 4, miRs-23a and -195 were also differentially expressed in the Validation Cohort. In the Test Cohort N= 6 each R and D for the Screening Array and N=7 each R and D for the Confirmatory PCR.

miR Expression
Screening Microarray (Test Cohort) Confirmatory PCR (Test Cohort) Confirmatory PCR (Validation Cohort)

miR ID Fold Change p -Value miR ID Fold Change p -Value miR ID Fold Change p -Value
R/D R/D R/D
miR-181b 11.38 0.002 miR-181b* N/A N/A miR-181b* No difference NS
miR-424 −4.38 0.027 miR-424 No difference NS miR-424 N/A N/A
miR-376a 5.41 0.028 miR-376a No difference NS miR-376a N/A N/A
miR-195 −2.91 0.029 miR-195 1.8 0.01 miR-195 1.5 0.03
miR-27a −4.18 0.032 miR-27a No difference NS miR-27a N/A NS
miR-23a −4.52 0.032 miR-23a 2.2 0.03 miR-23a 1.8 0.01
miR-103 3.69 0.044 miR-103 No difference NS miR-103 N/A N/A
miR-26a −14.92 0.044 miR-26a 1.4 0.04 miR-26a No difference NS
miR-142-3p 6.35 0.048 miR-142-3p No difference NS miR-142-3p N/A N/A
miR-15b −12.73 0.048 miR-15b 1.5 0.04 miR-15b −1.8 0.09
*

miR-181b could not be validated by this method in the Test Cohort, but was not significantly altered in the Validation cohort.

NS, not significant;

N/A: not applicable. These measurements were not performed.

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