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. Author manuscript; available in PMC: 2011 Nov 30.
Published in final edited form as: Bioorg Med Chem Lett. 2005 Jun 2;15(11):2724–2727. doi: 10.1016/j.bmcl.2005.04.008

Figure 2.

Figure 2

E2-penta exerts the most potent inhibition of sprouting. VEGF-stimulated spheroids were co-treated with 3 µM of E2-PROTAC, which contain the HIF-1α peptide of differing length. The percentage of angiogenic sprouting was quantified by measuring total number and length of sprouts as done previously.18