Figure 7.

Sperm adhesion to α6-expressing macrophage cells: effect of ADAM 3 disintegrin loop peptides. Mock-transfected (▧) and α6B-transfected P388D1 cells (▪) were, as indicated, preincubated for 30 min at 37°C with either an authentic (loop) or a scrambled mADAM 3 disintegrin loop peptide at a final concentration of 500 μM peptide. Sperm binding was then assayed as described in MATERIALS AND METHODS. The data represent the average number of sperm bound per cell. The data were averaged from three independent experiments. Bars represent the SE of the mean. Data for peptide treated groups were analyzed by Student's t test (**p < 0.01).