Table 1.
Comparison of adjusted p-values for 1000 correlated comparisons
| Na | p | PERMb | GPASSc | pACT | RAT | SLIDE |
|---|---|---|---|---|---|---|
| 500 | 3.15e–4 | 1.22e–1 | 1.32e–1 (1.08) | 1.12e–1 (0.92) | 1.40e–1 (1.15) | 1.35e–1 (1.11) |
| 3.20e–5 | 1.53e–2 | 1.52e–2 (0.99) | 1.32e–2 (0.86) | 1.13e–2 (0.74) | 1.49e–2 (0.97) | |
| 4.85e–6 | 2.28e–3 | 2.37e–3 (1.04) | 1.94e–3 (0.85) | 1.82e–3 (0.80) | 2.81e–3 (1.23) | |
| 5000 | 5.45e–4 | 2.31e–1 | 2.51e–1 (1.09) | 1.93e–1 (0.84) | 3.69e–2 (0.16) | 2.18e–1 (0.94) |
| 1.80e–5 | 1.03e–2 | 1.10e–2 (1.07) | 1.26e–2 (1.22) | 1.90e–3 (0.18) | 1.00e–2 (0.97) | |
| 1.00e–6 | 6.30e–4* | 5.75e–4 (0.91) | 4.74e–4 (0.75) | 7.99e–5 (0.13) | 5.70e–4 (0.90) |
a
Total number of individuals, including equal number of cases and controls.
b
Permutation p-values based on 50,000 independent permutations (*100,000 permutations).
c
Ratio between adjusted and permutation p-values are shown in parenthesis.