. Author manuscript; available in PMC: 2011 Nov 30.

Published in final edited form as: Ann Appl Stat. 2011 Sep 1;5(3):2052–2077. doi: 10.1214/11-AOAS469

Table 3.

Strong single SNP associations with T1D

SNP	Position	p-value	T1Dbase	Gene
rs6679677^*	chr1: 113.8–114.2 Mb	0	Yes	PTPN22
rs9405484	chr6: 1.4 Mb	1.33e–8	No	FOXC1
MHC^*	chr6: 25–35 Mb	0	Yes	MHC
rs6592988	chr7: 52.1 Mb	2.87e–7	Yes	COBL
rs11984645	chr8: 55.2 Mb	7.06e–11	No	MRPL15
rs11782342	chr8: 73.9 Mb	5.70e–12	No	KCNB2
rs11052552	chr12: 9.7 Mb	2.61e–7	Yes	CLEC2D
rs11171739^*	chr12: 54.8 Mb	2.35e–11	Yes	ERBB3
rs17696736^*	chr12: 109.8–110.9 Mb	0	Yes	CCDC63, NAP1
rs12924729^*	chr16: 11.1 Mb	1.01e–7	Yes	CLEC16A

SNPs showing strong associations (p-value < 5e–7) with T1D by single SNP test. p-value: nominal p-value of associations. T1Dbase: whether the locus is documented in T1Dbase. Gene: nearest gene.

Additional SNPs in its neighborhood also show strong marginal associations.