Figure 4. Integration of QA methods at different levels.

(a) the QA at alignment level including top alignments selection, top alignments clustering, and the conserved/non-conserved regions detection; (b) the QA at model level, including model evaluating and filtering by single-model QA methods, model ranking by consensus QA methods, and model clustering; (c) the hybridization of model and alignment QA. Note the broken line contour illustrates the model generation module.