Table 4.
Voltage-dependent gating parameters for late currents and tail currents in HEK-Nav1.6 cells induced by tefluthrin and deltamethrin.a
| Late Current | Tail Current | ||||
|---|---|---|---|---|---|
| Condition | n | V0.5 | K | V0.5 | K |
| + Tefluthrin (10 µM) | 19 | −55.0 ± 1.5 | 4.33 ± 0.26 | −52.0 ± 1.9 | 5.18 ± 0.32 |
| + Tefluthrin (100 µM) | 14 | −55.2 ± 1.3 | 4.78 ± 0.22 | −53.6 ± 1.3 | 5.40 ± 0.21 |
| + Deltamethrin (10 µM) | 16 | −48.2 ± 1.5 | 4.97 ± 0.37 | −46.6 ± 1.4 | 5.93 ± 0.42 |
a
Values are means ± SE calculated from fits of individual data sets obtained in the presence of tefluthrin or deltamethrin to the Boltzmann equation (see Fig. 4) ; V0.5, midpoint potential (mV) for voltage-dependent activation or inactivation; K, slope factor; n, number of replicate experiments.