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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Biochem J. 2011 Dec 15;440(3):385–395. doi: 10.1042/BJ20102148

Figure 3. Adiponectin promotes PTP1B expression.

Figure 3

A) Western blot and (B) quantitative RT-PCR analysis of PTP1B expression in Ad−/− mice and wild-type (WT) mice demonstrates reduced PTP1B expressed in Ad−/− mice compared with wild-type mice. (*p < 0.05 vs. WT). C) Data from quantitative RT-PCR shows PTP1B expression in rat HSCs after treatment with leptin (Lep, 100 ng/ml), adiponectin (Adi, 10 μg/ml), both (LA) or neither (Utx). Leptin suppressed PTP1B mRNA expression, while adiponectin stimulated PTP1B mRNA expression, whether administered alone or in the presence of leptin (*p < 0.05 vs. untreated).