Skip to main content
. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Eur Urol. 2011 Sep 10;61(1):78–84. doi: 10.1016/j.eururo.2011.05.065

Table 3.

Association of nocturia and depression (Center for Epidemiological Studies Depression Scale ≥5) stratified by age, antidepressant use, and sleep interference due to urinary symptoms: odds ratios and 95% confidence intervals

Men
Women
Characteristic Unadjusted, odds
ratio (95% CI)
Multivariate,*
odds ratio (95%
CI)
Unadjusted,
odds ratio (95%
CI)
Multivariate,**
odds ratio (95%
CI)
Age, yr

 30–49 4.26 (2.33–7.81) 3.25 (1.81–5.84) 3.53 (2.26–
5.54)
2.34 (1.46–
3.75)
 50–64 2.25 (1.30–3.91) 2.45 (1.31–4.57) 1.38 (0.85–
2.25)
1.15 (0.69–
1.89)
 ≥65 2.53 (0.99–6.47) 1.48 (0.69–3.16) 1.72 (0.90–
3.31)
1.48 (0.68–
3.23)
p interaction 0.266 0.630 0.013 0.030
SSRI/SNRI
use
 No 2.54 (1.72–3.76) 2.10 (1.33–3.33) 2.00 (1.42–
2.81)
1.59 (1.09–
2.33)
 Yes 3.47 (1.43–8.41) 2.66 (1.15–6.16) 3.40 (1.79–
6.45)
2.52 (1.31–
4.84)
p interaction 0.516 0.830 0.131 0.175
Sleep
interference
 No 2.82 (1.63–4.88) 2.43 (1.41–4.20) 1.40 (0.95–
2.07)
1.10 (0.74–
1.64)
 Yes 1.84 (0.76–4.46) 2.18 (0.73–6.53) 4.15 (2.25–
7.67)
3.37 (1.63–
6.94)
p interaction 0.428 0.635 0.002 0.009

CI = confidence interval; SSRI/SNRI = selective serotonin reuptake inhibitor/serotonin–norepinephrine reuptake inhibitor.

*

Adjusted for age, race/ethnicity, socioeconomic status, physical activity, smoking, alcohol consumption, and arthritis.

**

Adjusted for age race/ethnicity, socioeconomic status, smoking, alcohol consumption, heart disease, and diabetes.