. Author manuscript; available in PMC: 2012 Dec 18.

Published in final edited form as: Toxicology. 2011 Sep 6;290(2-3):157–169. doi: 10.1016/j.tox.2011.08.021

Table 3. Thymic T cell differentiation at 48 weeks of age.

Thymus	sex	0 μg/kg mean ± SEM	2.5 μg/kg mean ± SEM	5.0 μg/kg mean ± SEM

CD4^-CD8^- (%)	♀	17.1 ± 0.6	18.6 ± 1.2	21.8 ± 1.2^*
CD4^-CD8^- (%)	♂	13.2 ± 0.8	12.2 ± 0.8	15.0 ± 1.2

CD4⁺CD8⁺ (%)	♀	67.8 ± 1.6	63.3 ± 1.4	62.3 ± 2.0
CD4⁺CD8⁺ (%)	♂	65.0 ± 1.1	64.7 ± 1.3	58.8 ± 1.4^*

CD4^-CD8⁺ (%)	♀	5.1 ± 1.0	3.9 ± 0.3	3.6 ± 0.2
CD4^-CD8⁺ (%)	♂	7.7 ± 0.3	8.4 ± 0.6	9.4 ± 0.7

CD4⁺CD8^- (%)	♀	10.0 ± 1.0	14.2 ± 1.7	12.4 ± 1.3
CD4⁺CD8^- (%)	♂	14.2 ± 0.4	14.7 ± 0.5	16.8 ± 1.2

N≥6 mice/treatment/sex;

p<0.05, Dunnett's test.