Table 6. Lymph node T cell populations at 48 weeks of age.
Lymph node | sex | 0 μg/kg mean ± SEM |
2.5 μg/kg mean ± SEM |
5.0 μg/kg mean ± SEM |
---|---|---|---|---|
CD4+CD8- (%) | ♀ | 27.7 ± 3.1 | 27.3 ± 1.2 | 24.4 ± 1.9 |
♂ | 28.4 ± 1.1 | 32.0 ± 2.3 | 37.7 ± 1.1* | |
| ||||
CD4-CD8+ (%) | ♀ | 20.1 ± 3.4 | 13.7 ± 1.5 | 11.1 ± 0.9* |
♂ | 24.4 ± 2.0 | 24.6 ± 1.5 | 19.3 ± 1.0* | |
| ||||
CD4-CD8- (%) | ♀ | 51.4 ± 6.4 | 58.3 ± 2.5 | 63.9 ± 2.2 |
♂ | 43.2 ± 2.6 | 40.0 ± 2.9 | 39.7 ± 1.3 | |
| ||||
CD4+Vβ17TcR+ (%) | ♀ | 3.6 ± 0.3 | 4.9 ± 1.0 | 5.4 ± 0.5 |
♂ | 6.1 ± 0.3 | 7.3 ± 0.9 | 8.7 ± 0.8* | |
| ||||
CD3+Vβ3TcR+ (%) | ♀ | 5.2 ± 0.4 | 6.4 ± 1.0 | 8.1 ± 1.0* |
♂ | 5.1 ± 0.4 | 6.4 ± 1.0 | 8.4 ± 1.2* | |
| ||||
CD4+CD25+ (%) | ♀ | 8.7 ± 1.0 | 6.8 ± 1.0 | 6.1 ± 0.4 |
♂ | 10.2 ± 1.2 | 13.0 ± 2.0 | 7.2 ± 1.8 |
N≥6 mice/treatment/sex;
p<0.05, Dunnett's test.