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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Am J Transplant. 2011 Aug 29;11(12):2593–2602. doi: 10.1111/j.1600-6143.2011.03720.x

Figure 4. Transplantation of Gal-deficient islets results in superior graft function and more rapid return of euglycemia.

Figure 4

(a-b) WT islet recipients (a) most often experienced primary graft dysfunction, while transplantation of GTKO NPIs (b) resulted in prolonged insulin-independent normoglycemia, as shown in this representative pair. (c) Time to insulin independence was significantly shorter following transplantation of GTKO NPIs (p=0.03); however, duration of rejection-free survival (d) was similar for the two treatment groups (p=0.3). In (c), censored events represent recipient sacrifice. P-values calculated using logrank test.