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. Author manuscript; available in PMC: 2011 Nov 30.
Published in final edited form as: J Thromb Haemost. 2010 Nov;8(11):2394–2403. doi: 10.1111/j.1538-7836.2010.04035.x

Table 1.

The association between F7 genotypes and FVIIag, and FVIIc levels in NPHS-II study.

SNPs Genotype n FVIIag % (SE) P-value n FVIIc % (SE) P-value
rs555212 AA 1522 124 (0.86) 1594 105 (0.69)
AG 950 137 (1.09) 1025 114 (0.87)
GG 132 147 (2.92) 5.37E-34 142 125 (2.33) 4.46E-26

rs762635 AA 1530 124 (0.86) 1602 105 (0.69)
AC 947 137 (1.09) 1022 114 (0.87)
CC 127 147 (2.98) 2.21E-33 137 124 (2.38) 2.29E-25

rs510317 GG 1483 125 (0.88) 1555 105 (0.71)
GA 967 136 (1.09) 1041 113 (0.87)
AA 154 143 (2.72) 2.99E-23 165 120 (2.18) 1.81E-17

I/D 323* A1A1 2084 134 (0.72) 2221 114 (0.57)
A1A2 499 112 (1.48) 517 91 (1.18)
A2A2 21 95 (7.21) 4.59E-62 23 71 (5.57) 1.11E-78

rs1475931 TT 1764 130 (0.82) 1871 109 (0.65)
TG 756 129 (1.25) 801 110 (1.00)
GG 84 131 (3.74) 0.880 89 115 (3.00) 0.085

rs6046 GG 2090 135 (0.71) 2226 114 (0.56)
GA 493 110 (1.47) 510 89 (1.17)
AA 21 93 (7.13) 4.87E-79 25 71 (5.27) 4.58E-98

rs3211719 AA 1625 130 (0.85) 1726 109 (0.68)
AG 850 129 (1.18) 899 109 (0.95)
GG 129 136 (3.02) 0.059 136 115 (2.43) 0.023
*

A1-del, A2-ins; FVIIag, Factor VII antigen; FVIIc, factor VII coagulant activity.