Table 1.
SNPs | Genotype | n | FVIIag % (SE) | P-value | n | FVIIc % (SE) | P-value |
---|---|---|---|---|---|---|---|
rs555212 | AA | 1522 | 124 (0.86) | 1594 | 105 (0.69) | ||
AG | 950 | 137 (1.09) | 1025 | 114 (0.87) | |||
GG | 132 | 147 (2.92) | 5.37E-34 | 142 | 125 (2.33) | 4.46E-26 | |
| |||||||
rs762635 | AA | 1530 | 124 (0.86) | 1602 | 105 (0.69) | ||
AC | 947 | 137 (1.09) | 1022 | 114 (0.87) | |||
CC | 127 | 147 (2.98) | 2.21E-33 | 137 | 124 (2.38) | 2.29E-25 | |
| |||||||
rs510317 | GG | 1483 | 125 (0.88) | 1555 | 105 (0.71) | ||
GA | 967 | 136 (1.09) | 1041 | 113 (0.87) | |||
AA | 154 | 143 (2.72) | 2.99E-23 | 165 | 120 (2.18) | 1.81E-17 | |
| |||||||
I/D 323* | A1A1 | 2084 | 134 (0.72) | 2221 | 114 (0.57) | ||
A1A2 | 499 | 112 (1.48) | 517 | 91 (1.18) | |||
A2A2 | 21 | 95 (7.21) | 4.59E-62 | 23 | 71 (5.57) | 1.11E-78 | |
| |||||||
rs1475931 | TT | 1764 | 130 (0.82) | 1871 | 109 (0.65) | ||
TG | 756 | 129 (1.25) | 801 | 110 (1.00) | |||
GG | 84 | 131 (3.74) | 0.880 | 89 | 115 (3.00) | 0.085 | |
| |||||||
rs6046 | GG | 2090 | 135 (0.71) | 2226 | 114 (0.56) | ||
GA | 493 | 110 (1.47) | 510 | 89 (1.17) | |||
AA | 21 | 93 (7.13) | 4.87E-79 | 25 | 71 (5.27) | 4.58E-98 | |
| |||||||
rs3211719 | AA | 1625 | 130 (0.85) | 1726 | 109 (0.68) | ||
AG | 850 | 129 (1.18) | 899 | 109 (0.95) | |||
GG | 129 | 136 (3.02) | 0.059 | 136 | 115 (2.43) | 0.023 |
A1-del, A2-ins; FVIIag, Factor VII antigen; FVIIc, factor VII coagulant activity.