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Echocardiographic parameters in DSS rats with or without doxercalciferol. (A) Doxercalciferol treated animals showed a significant reduction in PWd, (B) as well as a marked improvement in fractional shortening (FS) compared to the vehicle group. (C) Left ventricular (LV) mass is also significantly reduced with doxercalciferol treatment. PWd=posterior wall thickness in diastole, ND=normal diet, HS=high salt diet, V=vehicle, D=doxercalciferol. *p<0.05. N=6–9.
