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. 2011 Dec;138(6):581–592. doi: 10.1085/jgp.201110683

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© 2011 Trudeau et al.

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Figure 3. — hERG1a NTR polypeptides regulate deactivation time course of hERG1a/hERG1b channels. (A–F) Whole cell patch-clamp recording of currents from hERG1a/hERG1b and NTR polypeptides, as indicated. The voltage protocol was a step to 20 mV for 1 s, followed by a step to −40 mV for 5 s. The holding potential was −80 mV. (G) Box plot of deactivation time constant (τ) derived from single-exponential fits to current relaxations at −40 mV (after the pulse to 20 mV). Time courses of currents from A and C–F were significantly different from those in B (P < 0.01; ANOVA). Bars in A–F, 1 s; n ≥ 6.