Table II.

Dwell time analysis of the wild-type single channel showing the effect of membrane stretch force on different states

[Ca2+]	Normalized dwell times of different states under 150-mmHg pressure (mean ± SD)			No. of patches
	C1	C2	O
M
10−5	0.21 ± 0.082	0.84 ± 0.24	1.3 ± 0.22	3
10−6	0.13 ± 0.031	1.0 ± 0.59	1.9 ± 0.78	5

Dwell times in different states under 150-mmHg pressure at two different [Ca²⁺] normalized to those without pressure (Fig. 2 B, top). Unity would indicate no change. As shown clearly, C1 is significantly reduced by pressure, whereas C2 and O are mildly affected. Note that the missed short C2 likely caused an overestimation of O.