Table 1.
Definitions and values of model parameters. (Parameters are numbers (age classes), proportions or rates (per person per year). Control variables are defined in the text.)
| parameters | point value | definition |
|---|---|---|
| β | 13 | average number of contacts made annually between each infectious TB patient and all other individuals in the population (value adjusted to fit equilibrium incidence) |
| μ | 0.013 | death rate from causes other than TB |
| μi | 0.25 | death rate from infectious TB |
| μn | 0.1 | death rate from non-infectious TB |
| m | 20 | number of age classes (used with μ to construct an age-dependent survivorship curve) |
| n | 3 | number of age classes occupied by children |
| nc | 0.1 | rate at which TB patients self-cure (in the absence of chemotherapy) |
| νf | 0.9 | rate at which latently infected people progress to active TB, fast (f, progressive primary disease) or slow (s, endogenous reactivation) |
| νs | 0.00011 | |
| pc | 0.05 | proportion of newly infected people, children or adults, who develop progressive primary TB (whether infectious or non-infectious) |
| pa | 0.15 | |
| σc | 0.1 | proportion of patients, children or adults, who develop infectious pulmonary TB |
| σa | 0.6 | |
| x | 0.35 | proportion of (exogenously) reinfected latents who develop active TB |