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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Arthritis Care Res (Hoboken). 2011 Oct;63(10):1415–1424. doi: 10.1002/acr.20550

Table 3.

Patterns of new DMARD use and co-therapies in RA patients (1998-2005)

COHORTS
Characteristics TennCare
(n=4383)
KPNC
(n=5695)
PACE
(2133)
MAX/MED
(n=20265)
DMARDs
1. First MTX 1668 (38.1%) 1359 (23.9%) 885 (41.5%) 6741 (33.3%)
2. New MTX 660 (15.1%) 1443 (25.3%) 298 (14.0%) 3686 (18.2%)
3. New HCQ/SSZ 492 (11.2%) 689 (12.1%) 112 (5.3%) 1698 (8.4%)
4. New LEF 407 (9.3%) 745 (13.1%) 176 (8.3%) 1835 (9.1%)
5. New anti-TNF 1156 (26.4%) 1459 (25.6%) 662 (31.0%) 6305 (31.1%)
Co-therapies use the day
before DMARD initiation
 • Corticosteroids 1373 (31.1%) 1822 (32.0%) 521 (24.4%) 5789 (28.6%)
 • NSAIDs 1670 (38.1%) 2010 (35.3%) 675 (31.7%) 7852 (38.8%)
 • Narcotics 1424 (32.5%) 872 (15.3%) 349 (16.4%) 6048 (29.8%)

DMARD: disease modifying anti-rheumatic drug; MTX: methotrexate; HCQ: hydroxychloroquine; SSZ: sulfasalazine; LEF: leflunomide; TNF: Tumor necrosis factor; NSAIDs: nonsteroidal anti-inflammatory drugs TennCare: Tennessee’s Medicaid program; KPNC: Kaiser Permanente Northern California program; PACE: Pennsylvania Pharmaceutical Assistance Contract for Elderly program; MAX/MED: Medicaid and/or Medicare program from 49 US states.