Table 3.
Patterns of new DMARD use and co-therapies in RA patients (1998-2005)
| COHORTS |
||||
|---|---|---|---|---|
| Characteristics | TennCare (n=4383) |
KPNC (n=5695) |
PACE (2133) |
MAX/MED (n=20265) |
| DMARDs | ||||
| 1. First MTX | 1668 (38.1%) | 1359 (23.9%) | 885 (41.5%) | 6741 (33.3%) |
| 2. New MTX | 660 (15.1%) | 1443 (25.3%) | 298 (14.0%) | 3686 (18.2%) |
| 3. New HCQ/SSZ | 492 (11.2%) | 689 (12.1%) | 112 (5.3%) | 1698 (8.4%) |
| 4. New LEF | 407 (9.3%) | 745 (13.1%) | 176 (8.3%) | 1835 (9.1%) |
| 5. New anti-TNF | 1156 (26.4%) | 1459 (25.6%) | 662 (31.0%) | 6305 (31.1%) |
| Co-therapies use the day before DMARD initiation |
||||
| • Corticosteroids | 1373 (31.1%) | 1822 (32.0%) | 521 (24.4%) | 5789 (28.6%) |
| • NSAIDs | 1670 (38.1%) | 2010 (35.3%) | 675 (31.7%) | 7852 (38.8%) |
| • Narcotics | 1424 (32.5%) | 872 (15.3%) | 349 (16.4%) | 6048 (29.8%) |
DMARD: disease modifying anti-rheumatic drug; MTX: methotrexate; HCQ: hydroxychloroquine; SSZ: sulfasalazine; LEF: leflunomide; TNF: Tumor necrosis factor; NSAIDs: nonsteroidal anti-inflammatory drugs TennCare: Tennessee’s Medicaid program; KPNC: Kaiser Permanente Northern California program; PACE: Pennsylvania Pharmaceutical Assistance Contract for Elderly program; MAX/MED: Medicaid and/or Medicare program from 49 US states.