Table 3.
Overall Positive Predictive Value for GI Perforation
| Total Identified Cases Based on Claims Database* | Cases Included in Chart Review Validation Study | Positive Predictive Value | ||||
|---|---|---|---|---|---|---|
| Total | Confirmed | Unconfirmed | ||||
| N | N | N | N | % | (95% Confidence Interval)^ | |
| GI site | ||||||
| Upper | 244 | 27 | 27 | 0 | 100.0% | (100% – 100%) |
| Esophagus | 28 | 5 | 5 | 0 | 100.0% | (100% – 100%) |
| Stomach | 216 | 22 | 22 | 0 | 100.0% | (100% – 100%) |
| Lower | 468 | 65 | 59 | 6 | 90.8% | (90.0% – 96.5%) |
| Small intestine | 5 | 1 | 1 | 0 | 100.0% | (100% – 100%) |
| Large intestine | 145 | 17 | 16 | 1 | 94.1% | (71.3% – 100%) |
| Unspecified | ||||||
| lower GI | 325 | 47 | 42 | 5 | 89.4% | (76.9% – 96.5%) |
| Overall | 704 | 92 | 86 | 6 | 93.5% | (86.3% – 97.6%) |
Identified cases: GI perforation cases identified from Premier inpatient database based on algorithm identified in Table 1
Cases included in the validation study: GI perforation cases being validated using chart review data based on physicians’ independent review
*
Sum of individual codes may exceed count in broader categories as patients may have multiple codes
^
95% confidence intervals were approximated using the binomial distribution