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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Toxicol Environ Health A. 2011 Jan;74(13):828–837. doi: 10.1080/15287394.2011.570225

Figure 1. NAC enhances plasma NOx concentrations following DE exposures.

Figure 1

A) Animals exposed to whole DE (approximately 3.2 ppm NO) with or without NAC for 1 hr (N=6/gp). B) Plasma NOx levels from animals exposed to whole DE with or without NAC for 2 hr (N=6/gp). C) Plasma NOx concentrations in rat plasma following 1 hr exposure to a pure NO (0, 3 and 10 ppm) atmosphere (N=6–10/gp). In addition, in a smaller cohort of rats, NOx levels were determined at 2 hr post exposure to 10 ppm NO (N=2) and 4 hr post exposure to 10 ppm NO (N=4). D) Pretreatment with NOS inhibitor L-NNA in filtered air or 10 ppm NO-exposed rats. Panels A and B, * p<0.05 vs FA/Saline and FA/NAC control,

† p<0.05 vs. DE/Saline; Panel C,

* p<0.05 vs Filtered Air and 4 hr post-exposure; Panel D,

* p<0.05 vs 0 ppm, † p<0.05 vs. 0 ppm + L-NNA.