Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Oct 6;3:1014–1024. doi: 10.1093/gbe/evr023

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

The Author(s) 2011. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

FIG. 4.— — Examples illustrating dosage sensitivity of CNV genes. Expression indicates normalized estimates from BAGEL analysis. For all panels, copy number is higher in PS2 than in PS1. Diamonds represent genes, with credible intervals shown. The expression levels are normalized. (A) Dosage-sensitive gene Cyp6g1 shows a copy-number increase and higher expression level in PS2 relative to PS1. Its expression level is also higher in PS2/PS3 heterozygotes compared with PS1/PS3, suggesting nonrecessive phenotype of Cyp6g1 CNV gene. (B) Dosage-sensitive gene CG31636 shows a copy-number increase and higher expression level in PS2 relative to PS1. Its expression level is not different between PS2/PS3 and PS1/PS3 heterozygotes, suggesting recessive phenotype of CG31636 CNV gene. (C) Dosage-reversed gene CG15649 shows a copy-number increase but lower expression level in PS2 relative to PS1.