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. 2011 Nov 17;2011:253048. doi: 10.1155/2011/253048

Figure 2.

Figure 2

Models of HNF4α-triggered formation of tight junctions and microvilli in F9 cells. (a) In an undifferentiated state, several junctional proteins are accumulated to premature junctions. (b) HNF4α provokes the formation of junctional complexes and microvilli via induction of expression of occludin [OCLN], claudin-6 [CLDN6], claudin-7 [CLDN7], and ezrin/radixin/moesin-binding phosphoprotein 50 [EBP50].