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. 2011 Nov 17;2012:236564. doi: 10.1155/2012/236564

Figure 3.

Figure 3

Dietary supplementation with n-3 PUFA decreases histological inflammatory parameters in jejunum of BALB/c-sensitized mice. BALB/c mice received 5% n-3 PUFA (control group) or 25% n-3 PUFA (N-3 PUFA group) as source of lipids in their diet 21 days before the sensitization. BALB/c mice were sensitized (allergic, OVA+) or not (nonallergic, OVA−) with OVA. Seven days after the booster, all mice received OVA diet. After 7 days, the mice were sacrificed and the intestine was taken for histology analyses. (a) Nonallergic control; (b) allergic control; (c) nonallergic n-3 PUFA; (d) allergic n-3 PUFA. Bar = 50 μm. In (b), long arrows show eosinophils, short arrows show Paneth cells, and asterisks show submucosal edema. In (e), data are reported as means ± SEM of number of eosinophils for 5 animals in each group. *P < 0.05 compared to nonallergic group (OVA−) with the same diet, and **P < 0.05 compared to allergic control group (ANOVA-Tukey).