Table 2.

Analysis for correlations between ERK1/2 and classical biomarkers*.

		ERK1/2
Patients group	CSF marker	r	P value	P value summary
Whole sample (n = 86)#	Aβ 1-42	−0.436	< 0.0001	Significant
	t-Tau	0.404	0.0001	Significant
	p-Tau	0.384	0.0003	Significant
	Age	0.0001	0.999	n.s.
ND (n = 14)#	Aβ 1-42	−0.0242	0.9346	n.s.
	t-Tau	−0.174	0.5528	n.s.
	p-Tau	−0.0022	0.9941	n.s.
	Age	0.0726	0.8052	n.s.
MCI-stable (n = 20)#	Aβ 1-42	0.0947	0.6912	n.s.
	t-Tau	0.399	0.0816	n.s.
	p-Tau	0.433	0.0563	n.s.
	Age	0.0845	0.7231	n.s.
MCI-AD (n = 20)#	Aβ 1-42	−0.0992	0.6772	n.s.
	t-Tau	0.325	0.1623	n.s.
	p-Tau	0.0248	0.9173	n.s.
	Age	0.171	0.4723	n.s.
AD (n = 32)#	Aβ 1-42	−0.544	0.0013	Significant
	t-Tau	0.176	0.3343	n.s.
	p-Tau	0.161	0.3789	n.s.
	Age	−0.136	0.457	n.s.

*Spearman correlation coefficients (r) and P values (two tailed) are indicated.

^#ERK1/2 measurements below LLOD (n = 9) were excluded from the correlation analysis.