Table 3.
Genes with a significant induction at the transcript level at pH 5.7
| ORF# | Gene | Protein functiona | 1. array | 2. array | 3. array | 4. array | Average fold reg. | SD | COGb |
|---|---|---|---|---|---|---|---|---|---|
| CAC0029 | Distantly related to cell wall-associated hydrolase, similar to yycO B. subtilis | 2.1 | 1.5 | 7.5 | 3.2 | 3.6 | 2.7 | S | |
| CAC0149 | Hypothetical protein | 5.9 | 5.2 | 14.5 | 10.1 | 8.9 | 4.3 | – | |
| CAC0164 | ABC transporter, ATP binding protein | 2.4 | 2.0 | 9.4 | 2.9 | 4.2 | 3.5 | V | |
| CAC0231 | Transcriptional regulator of sugar metabolism | 3.5 | 2.7 | 12.1 | 3.7 | 5.5 | 4.4 | K,G | |
| CAC0232 | fruB | 1-phosphofructokinase | 2.2 | 1.9 | 11.8 | 2.9 | 4.7 | 4.8 | G |
| CAC0233 | PTS system, IIA component | 2.5 | 2.0 | 18.2 | 2.3 | 6.2 | 8.0 | G,T | |
| CAC0234 | PTS system, fructoso-specific IIBC component | 2.2 | 2.1 | 8.1 | 3.0 | 3.9 | 2.9 | G | |
| CAC0360 | Transcriptional regulator | 3.1 | 2.6 | 6.5 | 5.6 | 4.5 | 1.9 | K | |
| CAC0407 | PP2C phosphatase family | 2.7 | 2.1 | 4.6 | 3.5 | 3.2 | 1.1 | T | |
| CAC0409 | Hypothetical protein | 2.1 | 1.9 | 5.7 | 3.2 | 3.2 | 1.8 | – | |
| CAC0410 | Hypothetical protein | 2.0 | 1.8 | 5.6 | 2.6 | 3.0 | 1.8 | S | |
| CAC0411 | Hypothetical protein | 2.8 | 2.3 | 7.3 | 5.3 | 4.4 | 2.3 | S | |
| CAC0412 | TPR-repeat-containing protein | 2.0 | 1.7 | 5.5 | 3.9 | 3.3 | 1.8 | R | |
| CAC0427 | Glycerol-3-phosphate ABC transporter, permease component | 3.1 | 3.1 | 5.7 | 2.9 | 3.7 | 1.3 | G | |
| CAC0428 | Sugar permease | 4.2 | 2.7 | 11.2 | 3.5 | 5.4 | 3.9 | G | |
| CAC0429 | Glycerol-3-phosphate ABC transporter, periplasmic component | 4.6 | 3.3 | 9.2 | 5.7 | 5.7 | 2.5 | G | |
| CAC0430 | Glycerophosphoryl diester phosphodiesterase | 2.2 | 3.5 | 7.1 | 6.8 | 4.9 | 2.4 | C | |
| CAC0742 | Phosphatase domain-containing protein | 2.2 | 1.8 | 6.3 | 3.1 | 3.3 | 2.0 | I | |
| CAC0946 | ComE-like protein | 2.8 | 2.4 | 4.6 | 3.9 | 3.4 | 1.0 | R | |
| CAC1081 | Hypothetical protein | 2.1 | 2.1 | 13.0 | 5.6 | 5.7 | 5.1 | S | |
| CAC1230 | Hypothetical protein | 2.6 | 2.6 | 6.9 | 2.3 | 3.6 | 2.2 | – | |
| CAC1231 | Predicted dehydrogenase | 2.0 | 1.7 | 7.1 | 3.8 | 3.6 | 2.5 | R | |
| CAC1547 | trxA | Thioredoxin | 4.1 | 3.4 | 8.3 | 6.8 | 5.6 | 2.3 | O |
| CAC1548 | trxB | Thioredoxin reductase | 3.3 | 3.6 | 6.9 | 5.2 | 4.8 | 1.7 | O |
| CAC1549 | bsaA | Glutathione peroxidase | 2.8 | 2.7 | 8.3 | 3.2 | 4.2 | 2.7 | O |
| CAC1583 | Predicted P-loop ATPase | 2.4 | 2.2 | 3.5 | 5.3 | 3.3 | 1.4 | E | |
| CAC1702 | Hypothetical protein | 3.2 | 3.0 | 4.9 | 5.0 | 4.0 | 1.1 | – | |
| CAC1703 | Methyl-accepting chemotaxis protein (fragment) | 2.4 | 2.5 | 5.2 | 4.4 | 3.6 | 1.4 | N,T | |
| CAC1704 | Hypothetical protein | 2.8 | 2.8 | 4.9 | 5.0 | 3.9 | 1.2 | – | |
| CAC2252 | Alpha-glucosidase | 1.9 | 2.3 | 7.1 | 5.2 | 4.1 | 2.5 | G | |
| CAC2342 | Predicted membrane protein | 4.1 | 4.3 | 2.1 | 3.4 | 3.5 | 1.0 | R | |
| CAC2365 | sspA | Small acid-soluble spore protein | 13.1 | 13.9 | 6.1 | – | 11.0 | 4.3 | – |
| CAC2438 | Predicted phosphatase | 5.3 | 4.7 | 3.4 | 4.8 | 4.5 | 0.8 | – | |
| CAC2601 | S-adenosylmethionine decarboxylase | 1.9 | 2.1 | 5.2 | 3.2 | 3.1 | 1.5 | E | |
| CAC2702 | Possible signal transduction protein | 4.0 | 3.7 | 3.6 | 5.0 | 4.1 | 0.6 | T | |
| CAC2709 | etfA | Electron transfer flavoprotein alpha-subunit | 2.3 | 2.0 | 5.4 | 2.4 | 3.0 | 1.6 | C |
| CAC2711 | bcd | Butyryl-CoA dehydrogenase | 2.0 | 1.8 | 6.1 | 2.4 | 3.1 | 2.0 | I |
| CAC2712 | crt | Enoyl-CoA hydratase | 2.1 | 1.8 | 7.2 | 2.9 | 3.5 | 2.5 | I |
| CAC2810 | Glucoamylase family protein | 2.7 | 2.2 | 10.1 | 4.9 | 5.0 | 3.6 | G | |
| CAC2873 | thlA | Acetyl-CoA acetyltransferase | 2.3 | 1.7 | 8.1 | 3.5 | 3.9 | 2.9 | I |
| CAC2938 | Hypothetical protein | 2.4 | 1.9 | 6.5 | 5.2 | 4.0 | 2.2 | R | |
| CAC3075 | buk | Butyrate kinase | 4.0 | 2.8 | 8.1 | 5.7 | 5.1 | 2.3 | C |
| CAC3076 | ptb | Phosphate butyryltransferase | 3.4 | 2.5 | 9.5 | 5.4 | 5.2 | 3.1 | C |
| CAC3236 | Transcriptional regulator | 2.7 | 2.1 | 13.2 | 8.5 | 6.6 | 5.3 | T,Q | |
| CAC3237 | msmX | Sugar ABC transporter, ATP binding protein | 2.5 | 2.2 | 10.9 | 8.1 | 5.9 | 4.3 | G |
| CAC3379 | Hypothetical protein | 3.6 | 3.5 | 5.6 | 6.3 | 4.7 | 1.4 | S | |
| CA_P0036 | Uncharacterized, ortholog of YgaT gene of B. subtilis | 90.4 | 19.0 | 270.0 | 200.0 | 144.9 | 111.8 | M | |
| CA_P0037 | Uncharacterized, ortholog of YgaS gene of B. subtilis | 114.9 | 54.1 | 451.9 | 250.0 | 217.7 | 176.3 | – | |
| CA_P0038 | Uncharacterized conserved protein, YCII family | 4.2 | 3.4 | 3.2 | 2.5 | 3.3 | 0.7 | S | |
| CA_P0072 | Hypothetical protein | 2.0 | 2.1 | 6.0 | 2.0 | 3.0 | 2.0 | – | |
| CA_P0073 | ABC ATPase containing transporter | 2.7 | 2.4 | 7.6 | 2.1 | 3.7 | 2.6 | V | |
| CA_P0074 | Hypothetical protein | 2.9 | 2.2 | 8.3 | 2.0 | 3.9 | 3.0 | – | |
| CA_P0149 | Xre family DNA-binding domain and TRP-repeat-containing protein | 2.6 | 2.6 | 4.2 | 3.2 | 3.1 | 0.8 | K |