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. 2011 Nov 30;6(11):e27535. doi: 10.1371/journal.pone.0027535

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This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Data for the 1,235 FHA-responsive elements from our 23 arrays were compared to data for the 920 elements previously described by Boldrick et al. from 16 arrays [20], whose expression in PBMCs displayed a ≥2.5-fold change from baseline (t = 0) in response to BpLPS (1 µg/ml) or to two heat-killed B. pertussis strains (BP338 and Minnesota 1 [BpeMin1]). The 143 elements common to both data sets are represented in a hierarchical cluster format. Each time course is represented by a triangle at the top of the Figure; the times of exposure are 0.5, 2, 4, and 6 hrs for all conditions except for FHA-4, in which the 4 hour time point is missing. The genes represented by at least two non-identical elements on the arrays are indicated in bold.