Table 1. Non-SNP features (above the horizontal line) and interactions (below the horizontal line) chosen by our adaptive prediction algorithm.
| Code | feature | cutoff fraction of occurrence | |||||||
| 0.01 | 0.05 | 0.1 | 0.2 | ||||||
| avg coef | CVcount | avg coef | CV count | avg coef | CV count | avg coef | CV count | ||
| ANTA07A | Waist girth (cm) | 2.97E−02 | 2 | 2.53E−02 | 4 | 2.88E−02 | 5 | 1.63E−02 | 7 |
| APASIU01 | Apolipoprotein A1 (mg/L) | NA | NA | 2.53E−04 | 4 | 2.17E−04 | 1 | NA | NA |
| APBSIU01 | Apolipoprotein B (mg/L) | 3.37E−05 | 3 | 8.38E−05 | 2 | NA | NA | NA | NA |
| BMI01 | Body mass index (kg/m2) | 3.23E−02 | 2 | 1.69E−02 | 2 | 2.74E−02 | 1 | 6.15E−02 | 1 |
| CENTERID.B | Field center | −3.51E−01 | 5 | −7.11E−01 | 7 | −2.35E−01 | 2 | NA | NA |
| CENTERID.D | Field center | −1.95E+00 | 10 | −2.18E+00 | 10 | −1.74E+00 | 8 | −1.31E+00 | 1 |
| CHOLMD02.1 | Meds that secondarily lower cholesterol | 8.14E+00 | 10 | 8.45E+00 | 10 | 8.20E+00 | 10 | 7.54E+00 | 10 |
| CIGT01.2 | Cigarette smoking status (% never) | 6.01E−01 | 6 | 8.89E−01 | 7 | 4.49E−01 | 4 | 6.28E−01 | 1 |
| CIGT01.3 | Cigarette smoking status (% never) | 9.73E−01 | 10 | 1.26E+00 | 9 | 8.92E−01 | 6 | 8.96E−01 | 2 |
| CIGTYR01 | Cigarette years of smoking | −6.29E−04 | 9 | −7.00E−04 | 8 | −5.54E−04 | 6 | NA | NA |
| ETHANL03 | Usual ethanol intake (g/week) | 5.60E−03 | 6 | 6.21E−03 | 4 | 2.28E−03 | 3 | NA | NA |
| INSSIU01 | Insulin (pmol/L) | 7.81E−04 | 2 | 6.11E−04 | 4 | 3.49E−04 | 4 | NA | NA |
| TCHSIU01 | Total cholesterol (mmol/L) | 5.84E−01 | 1 | 5.88E−01 | 2 | 5.80E−01 | 5 | 5.31E−01 | 10 |
| TRGSIU01 | Total triglycerides (mmol/L) | 3.58E−01 | 5 | 3.82E−01 | 9 | 3.11E−01 | 9 | 1.34E−01 | 4 |
| V1AGE01 | Age at first visit | 1.01E−01 | 9 | 1.31E−01 | 10 | 1.24E−01 | 10 | 1.03E−01 | 3 |
| WSTHPR01 | Waist-to-hip ratio | 1.73E+00 | 3 | 1.94E+00 | 2 | 4.54E+00 | 2 | 5.61E+00 | 2 |
| ANTA07A:TCHSIU01 | 8.10E−03 | 5 | 7.32E−03 | 4 | 8.17E−03 | 1 | NA | NA | |
| BMI01:TCHSIU01 | 3.13E−02 | 2 | 2.29E−02 | 1 | NA | NA | NA | NA | |
| BMI01:TRGSIU01 | 1.12E−02 | 1 | NA | NA | NA | NA | NA | NA | |
| CHOLMD021:ANTA07A | NA | NA | NA | NA | NA | NA | 7.32E−03 | 3 | |
| CHOLMD021:ANTA07A:TCHSIU01 | 1.05E−03 | 4 | NA | NA | 1.04E−03 | 1 | NA | NA | |
| ERHA21:ANTA07A | 7.04E−04 | 10 | 8.83E−04 | 10 | 7.56E−04 | 9 | 1.09E−03 | 4 | |
| ERHA21:APBSIU01 | 4.69E−06 | 1 | 1.10E−05 | 1 | NA | NA | NA | NA | |
| ERHA21:BMI01 | 2.38E−03 | 8 | 2.39E−03 | 10 | 3.17E−03 | 10 | 4.24E−03 | 9 | |
| ERHA21:BMI01:V1AGE01 | 7.31E−05 | 1 | NA | NA | NA | NA | NA | NA | |
| ERHA21:CENTERIDB | −3.66E−03 | 2 | NA | NA | NA | NA | NA | NA | |
| ERHA21:CIGT013 | NA | NA | NA | NA | 1.33E−03 | 1 | NA | NA | |
| ERHA21:INSSIU01 | 5.44E−05 | 1 | NA | NA | 4.75E−05 | 1 | 3.09E−05 | 1 | |
| ERHA21:TCHSIU01 | 5.37E−03 | 4 | 5.86E−03 | 6 | 9.13E−03 | 4 | NA | NA | |
| ERHA21:TRGSIU01 | 4.71E−03 | 4 | 2.57E−03 | 3 | 6.12E−03 | 1 | NA | NA | |
| ERHA21:V1AGE01 | 9.25E−04 | 5 | 1.50E−03 | 1 | 1.25E−04 | 1 | NA | NA | |
| ERHA21:WSTHPR01 | 5.09E−02 | 1 | NA | NA | NA | NA | NA | NA | |
| INSSIU01:CIGT012 | 3.32E−03 | 2 | 3.42E−03 | 1 | NA | NA | NA | NA | |
| INSSIU01:TCHSIU01 | NA | NA | 9.67E−04 | 1 | NA | NA | NA | NA | |
For each cutoff fraction of occurrence in the bootstrapped CART, average coefficient and the number of times the corresponding feature is selected over the 10-fold cross validation is presented. Results are shown for medication-adjusted mean arterial blood pressure.