Table 2.
CCD plan of coded value, the observed value and predicted value
| Run | X1 | X2 | X3 | Observed value (U/mL) | Predicted value (U/mL) | Residual |
|---|---|---|---|---|---|---|
| 1 | 1 | 1 | 1 | 305.0 | 300.59440 | 4.40560 |
| 2 | 1 | 1 | -1 | 270.0 | 269.50019 | 0.49981 |
| 3 | 1 | -1 | 1 | 266.7 | 263.28293 | 3.41707 |
| 4 | 1 | -1 | -1 | 271.7 | 264.68872 | 7.01128 |
| 5 | -1 | 1 | 1 | 280.0 | 278.74159 | 1.25841 |
| 6 | -1 | 1 | -1 | 250.0 | 245.14737 | 4.85263 |
| 7 | -1 | -1 | 1 | 241.7 | 233.93012 | 7.76988 |
| 8 | -1 | -1 | -1 | 236.7 | 232.83590 | 3.86410 |
| 9 | 1.682 | 0 | 0 | 285.0 | 290.12933 | -5.12933 |
| 10 | -1.682 | 0 | 0 | 238.4 | 244.96290 | -6.56290 |
| 11 | 0 | 1.682 | 0 | 290.0 | 292.56256 | -2.56256 |
| 12 | 0 | -1.682 | 0 | 241.7 | 250.82967 | -9.12967 |
| 13 | 0 | 0 | 1.682 | 256.7 | 262.73135 | -6.03135 |
| 14 | 0 | 0 | -1.682 | 230.0 | 235.66088 | -5.66088 |
| 15 | 0 | 0 | 0 | 280.0 | 291.33368 | -11.33368 |
| 16 | 0 | 0 | 0 | 296.7 | 291.33368 | 5.36632 |
| 17 | 0 | 0 | 0 | 300.0 | 291.33368 | 8.66632 |
| 18 | 0 | 0 | 0 | 283.3 | 291.33368 | -8.03368 |
| 19 | 0 | 0 | 0 | 290.0 | 291.33368 | -1.33368 |
| 20 | 0 | 0 | 0 | 300.0 | 291.33368 | 8.66632 |